If you have taken PRN De3 for years and encounter EyePromise De3 online, the new label can look like a different supplement. 

What changed in the United States?

PRN Vision Group, EyePromise and Avenova have been brought together under the EyePromise identity. EyePromise.com now presents De3 in a redesigned blue bottle and uses “new look, same formula” messaging.

Packaging changes do not reach every store at the same time. At the time of writing, EyeDropShop.com still sells PRN De3 Dry Eye Omega Benefits under the PRN name.

What should match if it is the same core formula?

If a future package changes any of these numbers, treat it as a formula update that deserves a fresh comparison—not merely a cosmetic redesign.

What should you check before buying?

• The daily serving: three softgels or gelcaps.
• The EPA and DHA amounts: 1,680 mg EPA and 560 mg DHA per full serving.
• Vitamin D3: 1,000 IU / 25 mcg per serving.
• The omega-3 form: re-esterified triglyceride (rTG).
• The bottle size: 90, 180 or 270 softgels
• The safety information: ingredients, allergens, seal, lot and expiration date.

Does the brand change alter the research?

The research is tied to the formula: EPA, DHA, ratio, rTG form, daily dose and trial results. If those specifications stay the same, a logo or bottle redesign does not change what the studies tested.

For the current science, read the balanced De3 evidence review. For the formula, visit the 3:1 EPA:DHA explainer. To compare other U.S. options, see PRN De3 vs HydroEye, EZ Tears, OcuSci and Omega-V.

Frequently asked questions

Is EyePromise De3 a different product from PRN De3?

EyePromise describes its redesign as “new look, same formula,” and the core daily EPA, DHA and vitamin D3 amounts match the current PRN bottle. 

Can I receive a different bottle from the one pictured?

Packaging can overlap during a transition. If the bottle differs, compare the seal, Supplement Facts, ingredients, serving, lot and expiration date, and contact Eye Drop Shop if anything is unclear.

Should I wait for the EyePromise bottle?

A name or package change alone is not a clinical reason to wait. What's important is the formula. If anything is unclear, contact Eye Drop Shop customer service.

Sources

• EyeDropShop U.S.: current PRN De3 listing
• EyePromise U.S.: De3 Omega Benefits
• EyePromise De3 communications

Branding and product information is current to July 2026 and should be rechecked when EyeDropShop's U.S. packaging or listing changes.