Quick answer: OPTASE HYLO Night offers preservative-free bedtime lubrication in a 5 g tube, with petrolatum, mineral oil, lanolin and supporting vitamin A. Systane Nighttime, Refresh P.M. and Retaine PM use different ointment bases. We like HYLO Night for its distinctive formula and place in the OPTASE routine; all can temporarily blur vision, so this is a bedtime comparison—not a daytime drop contest.
OPTASE US product imagery for night comparison

If a watery drop is not enough at bedtime, an ointment can be a useful next conversation. It is thicker, feels different and belongs in a part of the day when temporary blur is less disruptive. The question is not which product behaves most like a daytime drop. It is which bedtime lubricant makes sense for your needs.

Why ointments are different

Ointment bases use ingredients such as petrolatum and mineral oil to create a thicker lubricating layer. That can be appealing for overnight comfort, but it also explains why vision may blur after application. “No blur” is not a sensible blanket promise for this category.

Remove contact lenses and follow the directions for the amount and placement. Do not apply a large amount simply because you want longer relief. If you wake with persistent pain, significant redness or changed vision, get an assessment rather than assuming you need a thicker product.

Product Formula distinction Package/use consideration
OPTASE HYLO NightOPTASE HYLO Night Eye Ointment US packaging Petrolatum, mineral oil and lanolin base; vitamin A included Preservative-free 5 g tube; bedtime-oriented lubrication.
Systane NighttimeSystane Nighttime Eye Ointment product packaging Mineral oil 3% and white petrolatum 94% active ingredients Preservative-free 3.5 g tube.
Refresh P.M.REFRESH P.M.  Preservative-Free lubricating eye ointment product packaging Mineral oil 42.5% and white petrolatum 57.3% active ingredients Preservative-free 3.5 g tube.
Retaine PMRetaine PM product packaging Mineral oil 20% and white petrolatum 80% Preservative-free 5 g tube.

Why HYLO Night deserves your attention

OPTASE HYLO Night Eye Ointment US packaging

HYLO Night’s distinctive point is the combination of its ointment base with supporting vitamin A. That makes it more than simply a differently branded tube of the same mineral-oil/petrolatum ratio. Its 5 g format is also a useful practical feature.

We recommend it confidently as a bedtime option within the OPTASE range. The supporting vitamin A does not make it a treatment for vitamin deficiency, and it does not prove the product outperforms every simpler ointment. Read the complete HYLO Night guide for its role and directions.

Systane Nighttime: a familiar, credible alternative

Systane Nighttime Eye Ointment product packaging

Systane Nighttime has a petrolatum-dominant active-ingredient profile. It is another product we carry and a straightforward choice for people who already find its consistency comfortable. A familiar formula that suits you is not a poor purchase.

HYLO Night’s attraction is the different base and supporting ingredient profile, not the idea that every Systane user needs to upgrade. If lanolin sensitivity is relevant, examine the complete ingredients rather than just the active panel; an ingredient can appear elsewhere on the label.

Evening reading routine with OPTASE HYLO Night ointment

Refresh P.M.: a different mineral-oil balance

REFRESH P.M.  Preservative-Free lubricating eye ointment product packaging

Refresh P.M. lists a substantially higher mineral-oil proportion than Systane Nighttime, alongside white petrolatum. That is a genuine formulation difference, but percentages alone do not tell you which product will feel best to your eyes.

Some shoppers prefer a particular texture and return to it. We treat Refresh as a valid option in our store. HYLO Night becomes especially interesting when you want to explore its distinctive formula or keep the bedtime step within the OPTASE range.

Retaine PM: simple ingredients, different balance

Retaine PM product packaging

Retaine PM uses mineral oil 20% and white petrolatum 80% in a 5 g tube. It is a straightforward outside competitor in this category. Its simplicity is a feature for some shoppers, not evidence of a poor-quality product.

We would shortlist HYLO Night first if you want the supporting vitamin A formula and a coordinated OPTASE routine. That is a stronger reason to choose it than pretending an ointment with a different mineral-oil percentage must provide weaker relief.

How to make bedtime use more comfortable

Finish tasks that need clear vision before applying ointment. Wash your hands, avoid touching the tube tip to the eye or lashes, use the label-directed amount and recap. If you also use drops or prescribed medicine, confirm spacing and order; ointment is commonly used after other eye products.

Store the tube as instructed and observe its after-opening period. Do not use it simply because there is still plenty left if that period has passed. A thicker format still needs careful hygiene.

When another part of the routine needs attention

Morning dryness can have several causes, including environmental exposure or eyelid problems. Ointment may support lubrication, but it should not become the only response to recurring symptoms.

Ask whether warmth, lid hygiene or changes to airflow belong in the plan. The routine guide helps connect those steps. For daytime choices, use the OPTASE drop comparison rather than expecting an ointment to be your all-day solution.

Our recommendation

HYLO Night is a compelling bedtime choice when you value its formula and want that step within a broader OPTASE routine. Systane and Refresh remain useful alternatives we carry. Against Retaine PM, HYLO Night’s distinctive formula gives you a clear reason to explore it.

The best choice is comfortable, appropriately used and suitable for your ingredients and care needs. If you know you react to lanolin or another component, that matters more than any brand preference.

Frequently asked questions

Will HYLO Night blur my vision?

Temporary blur can occur with ointments. Bedtime use makes that less disruptive; do not drive or do tasks needing clear vision until it resolves.

Does vitamin A make it a treatment for deficiency?

No. Do not use an ointment as a substitute for assessment or nutritional treatment.

Is a higher mineral-oil percentage better?

Not automatically. Texture, tolerance and the whole formula matter.

Can I wear contacts with an ointment?

Remove lenses and follow the product directions. Ointments are not contact lens rewetting drops.

Make your eye care routine work better for you
Explore OPTASE HYLO Night Eye Ointment

Sources and further reading

Educational information, not a diagnosis or a substitute for your eye care professional's advice. Follow the directions on your US package. Stop use and seek medical advice for eye pain, vision changes, persistent redness or worsening symptoms. Eye drops, eyelid cleansers, makeup removers and masks are different products and are not interchangeable.

October 06, 2026
Tags: Dry Eye OPTASE

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